Diffusion tensor imaging of vastus lateralis in patients with inflammatory myopathies
Authors' conclusion
Addition of DWI or DTI did not add significantly in determining active inflammation in cases of myositis.
Study context
- Population
- Patients with myositis undergoing MRI of bilateral thighs with DWI/diffusion tensor imaging (DTI) protocol; biopsy of right vastus lateralis in a subset33 underwent vastus lateralis (VL) biopsy
- Participants
- 43 patients
- Outcome
- Association between DTI of vastus lateralis and histopathological findings; diagnostic performance of MRI variables in predicting histopathological outcomes
Methodological detailsprospective, observational
- Prospective
- Observational
Main finding
As reported in the abstract
- Average DWI apparent diffusion coefficient (ADC), mean ± SD
- 1.77 ± 0.35
- Average DTI ADC, mean ± SD
- 2.06 ± 0.35
- Average functional anisotropy (FA), mean ± SD
- 0.39 ± 0.17
- First eigenvalue, mean ± SD
- 2.96 ± 0.63
- Second eigenvalue, mean ± SD
- 2.05 ± 0.32
- Third eigenvalue, mean ± SD
- 1.20 ± 0.39
Observational data: associations, not effects.
Original publication
Diffusion tensor imaging of vastus lateralis in patients with inflammatory myopathies. Rheumatology (Oxford). Published 14 October 2024. doi:10.
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