Spondyloarthritis & psoriatic arthritis

Diagnostic delay in patients from the International Map of Axial Spondyloarthritis: geographic, sociodemographic and disease-related factors

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

In this global sample of axSpA patients the mean diagnostic delay was 7.4 years, and showed significant differences across regions. Younger age at symptom onset, female gender, diagnosis made by a rheumatologist, greater number of HCPs seen before diagnosis and history of uveitis were the parameters associated with a longer diagnostic delay in axSpA patients.

Study context

Population
Axial spondyloarthritis (axSpA) patients from 27 countries in the International Map of Axial Spondyloarthritis (IMAS) online survey, 2017–225,327 analysed
Participants
5,557 patients
Exposure
Europe vs North America vs Asia vs Latin America vs Africa
  • Europen = 3,294
  • North American = 752
  • Asian = 590
  • Latin American = 545
  • African = 146
Outcome
Diagnostic delay (age at diagnosis minus age at first symptom onset, patient-reported)
Methodological detailsonline survey, multinational (27 countries), univariable and multivariable linear regression
  • Online survey
  • Multinational (27 countries)
  • Univariable and multivariable linear regression

Main finding

As reported in the abstract

Diagnostic delay, overall

Mean diagnostic delay since symptom onset (years)

7.4

Median diagnostic delay (years)

4.0

Observational data: associations, not effects.

Further findings

Factors associated with longer diagnostic delay (final multivariable linear regression model)

Younger age at symptom onset (b)
−0.100
Female gender (b)
2.274
Diagnosed by a rheumatologist (b)
1.163
Greater number of heathcare professionals (HCPs) seen before diagnosis (b)
1.033
History of uveitis (b)
1.286

Original publication

Diagnostic delay in patients from the International Map of Axial Spondyloarthritis: geographic, sociodemographic and disease-related factors. Rheumatology (Oxford). Published 25 September 2024. doi:10.1093/rheumatology/keae521

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