Spondyloarthritis & psoriatic arthritis
Subclinical dactylitis is linked with active phenotype of psoriatic arthritis
Authors' conclusion
Subclinical dactylitis also represents a more active phenotype of PsA
Study context
- Population
- Psoriatic arthritis (PsA) patients of the PKUPsA cohort with complete US assessment of synovitis, tenosynovitis and soft tissue of both hands and feet
- Participants
- 223 patients
- Exposure
- Subclinical dactylitis vs clinical dactylitis vs no dactylitis
- Clinical dactylitisn = 90
- Subclinical dactylitisn = 26
- No-dactylitisn = 107reference
- Outcome
- Impact of subclinical dactylitis on PsA severity (clinical characteristics)
Methodological detailsPKUPsA cohort, ultrasound assessment of both hands and feet
- PKUPsA cohort
- Ultrasound assessment of both hands and feet
Main finding
As reported in the abstract
Subclinical dactylitis vs no dactylitis: disease activity
DAPSA score
27.2 vs. 16.1
P < 0.05
Subclinical dactylitis
Swollen joint count
4.5 vs. 2
P < 0.01
Subclinical dactylitis
Tender joint count
5 vs. 3
P < 0.05
Subclinical dactylitis
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | P value |
|---|---|---|
| Clinical dactylitis vs no dactylitisClinical dactylitis vs No-dactylitis | swollen joint count 4 vs. 2 | P < 0.01 |
| Clinical dactylitis vs no dactylitisClinical dactylitis vs No-dactylitis | tender joint count 4 vs. 3 | P < 0.05 |
| Clinical dactylitis vs no dactylitisClinical dactylitis vs No-dactylitis | median DAPSA 25.0 vs. 18.3 | P < 0.05 |
| Clinical or subclinical dactylitis (n=116) vs no dactylitisClinical or subclinical dactylitis vs No-dactylitis | tender joint count 4 vs. 2 | P < 0.01 |
| Clinical or subclinical dactylitis (n=116) vs no dactylitisClinical or subclinical dactylitis vs No-dactylitis | swollen joint count 4 vs 3 | P < 0.001 |
| Clinical or subclinical dactylitis (n=116) vs no dactylitisClinical or subclinical dactylitis vs No-dactylitis | median CRP 18.1 vs. 11.8 | P < 0.05 |
| Clinical or subclinical dactylitis (n=116) vs no dactylitisClinical or subclinical dactylitis vs No-dactylitis | median DAPSA 25.5 vs. 16.1 | P < 0.01 |
| Clinical or subclinical dactylitis (n=116) vs no dactylitisClinical or subclinical dactylitis vs No-dactylitis | swollen joint count excluding dactylitic digits 3 vs. 2 | P < 0.01 |
Original publication
Subclinical dactylitis is linked with active phenotype of psoriatic arthritis. Joint Bone Spine. Published 24 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →