Development of the paediatric society of the African league against rheumatism (PAFLAR) Juvenile Idiopathic Arthritis (JIA) registry and clinical profile of JIA in Africa from the PAFLAR JIA registry
Authors' conclusion
Our study highlights strategies involved in setting up a Pan-African paediatric rheumatology registry that embraces our broad diversity and the vast spectrum of JIA in Africa while comparing the various therapies available to our patients.
Study context
- Population
- Children with JIA under the care of PAFLAR collaborators across various regions in Africa177 female
- Participants
- 302 children
- Outcome
- Clinical profile of JIA in Africa
- Follow-up
- Initial diagnosis
Methodological detailsobservational, registry-based, descriptive, Collaborators trained to enter data in the existing PAFLAR REDCAP database
- Observational
- Registry-based
- Descriptive
- Collaborators trained to enter data in the existing PAFLAR REDCAP database
Main finding
As reported in the abstract
- Female
- 58.6% (177 of 302)
- Age at disease onset, median (range 3-11 years)
- 7 years
- Age at diagnosis, median (range 5-12 years)
- 8.5 years
- Delay in diagnosis, median (range 1-20.8 months)
- 6 months
- sJIA
- 18.9% (57)
- Oligoarticular JIA
- 19.2% (83)
- Polyarticular RF + ve
- 5% (15)
- Polyarticular RF-ve
- 17.9% (54)
- Enthesitis related arthritis (ERA)
- 18.2% (55)
- Psoriatic arthritis
- 7% (21)
- Undifferentiated JIA
- 5.6% (17)
- Therapy at diagnosis: NSAID
- 31.1%
- Therapy at diagnosis: synthetic DMARDs
- 18.1%
- Therapy at diagnosis: synthetic DMARDs + NSAIDs
- 17.5%
- Therapy at diagnosis: steroids
- 9.6%
- Therapy at diagnosis: bDMARDs
- 2.3%
- JADAS score, average (range 4.8-18.2)
- 10.3
- CHAQ score, average (range 0.7-2.0)
- 1.3
Observational data: associations, not effects.
Original publication
Development of the paediatric society of the African league against rheumatism (PAFLAR) JIA registry and clinical profile of JIA in Africa from the PAFLAR JIA registry. Pediatr Rheumatol Online J. Published 22 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →