Systematic Literature Review Informing Paediatric Rheumatology European Society/Childhood Arthritis and Rheumatology Research Alliance–Endorsed Recommendations for the Treat-to-Target Strategy in Juvenile Dermatomyositis
Authors' conclusion
This SLR provides a comprehensive overview of the current knowledge that served as the basis for the consensus definition of the overarching principles and recommendations for the T2T strategy in JDM.
Study context
- Population
- Published studies on the treat-to-target (T2T) strategy in juvenile dermatomyositis (JDM) (clinical trials, observational studies, case reports of > 2 patients, expert recommendations, systematic reviews) until March 2023220 articles included
- Outcome
- Evidence on T2T strategy in JDM
Methodological detailsGrading of Recommendations, Assessment, Development, and Evaluation (GRADE) quality assessment (modified), 14 research questions formulated by the steering committee, MEDLINE, Embase, Cochrane Central and Web of Science searched
- GRADE quality assessment (modified)
- 14 research questions formulated by the steering committee
- MEDLINE, Embase, Cochrane Central and Web of Science searched
Main finding
As reported in the abstract
Articles retrieved from databases
2714
Articles included in final review
220
Articles with strong evidence
2
Articles with moderate evidence
22
Original publication
Systematic Literature Review Informing Paediatric Rheumatology European Society/Childhood Arthritis and Rheumatology Research Alliance–Endorsed Recommendations for the Treat-to-Target Strategy in Juvenile Dermatomyositis. J Rheumatol. Published 15 April 2026. doi:10. 3899/ jrheum. 2025-1157
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