Pediatric rheumatology

Treating juvenile dermatomyositis to target: Paediatric Rheumatology European Society/Childhood Arthritis and Rheumatology Research Alliance-endorsed recommendations from an international task force

Ann Rheum DisPublished Recommendations

Methodological detailsinternational task force, systematic literature review, retrospective chart review, consensus voting (≥80% majority)
  • International task force
  • Systematic literature review
  • Retrospective chart review
  • Consensus voting (≥80% majority)

Recommendations

As issued by the authors

  1. Patients/parents and treaters share decisions in setting treatment targets and therapeutic strategies

  2. Inactive disease is the preferred target; minimal disease activity an alternative one

  3. Inactive disease targeted within 12 months after treatment start

  4. Interim targets: minimal and moderate clinical improvement within 6 weeks and 3 months, respectively; normalisation of muscle strength within 6 months

  5. High-dose GC remain fundamental initially; progressive tapering and discontinuation within 12 months through optimisation of concomitant immunomodulatory therapy

Original publication

Treating juvenile dermatomyositis to target: Paediatric Rheumatology European Society/Childhood Arthritis and Rheumatology Research Alliance-endorsed recommendations from an international task force. Ann Rheum Dis. Published 22 May 2025. doi:10.1016/j.ard.2025.04.024

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