Lupus & antiphospholipid syndrome
Determinants of social participation in patients living with systemic lupus erythematosus: the psychosocial lupus (Psy-LUP) multicentre study
Authors' conclusion
Social participation is frequently altered in patients with SLE and correlates with illness representations, time perspective and HR-QoL.
Study context
- Population
- Adult outpatients with systemic lupus erythematosus (SLE) enrolled in the multicentre psychosocial lupus (Psy-LUP) study92 women and eight men
- Participants
- 100 outpatients
- Outcome
- Determinants of social participation (Participation Scale)
Methodological detailsmulticentre, stepwise multivariate regression
- Multicentre
- Stepwise multivariate regression
Main finding
As reported in the abstract
Determinants of reduced social participation (multivariate linear regression)
- Female sex associated with reduced social participation
- p=0.006
- Smoking associated with reduced social participation
- p=0.04
- Osteoporotic fractures associated with reduced social participation
- p=0.03
- aCL antibodies associated with reduced social participation
- p=0.01
- 'Past Negative' time perspective associated with reduced social participation
- p=0.002
- Haematological involvement protective
- p=0.005
- 'Present Hedonistic' time perspective protective
- p=0.02
Observational data: associations, not effects.
Original publication
Determinants of social participation in patients living with systemic lupus erythematosus: the Psy-LUP multicentre study. RMD Open. Published 25 June 2025. doi:10. 1136/ rmdopen-2025-005661
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