Lupus & antiphospholipid syndrome
Clinical and laboratory differences in pediatric-onset versus adult-onset lupus nephritis: A retrospective cohort analysis
Authors' conclusion
pLN is characterized by more severe SLE clinical manifestations.
Study context
- Population
- Adult LN patients treated at the University Hospital in Kraków, Poland, 2012–2022, meeting the 2019 EULAR/ACR criteria for systemic lupus erythematosus (SLE)
- Participants
- 343 patients
- Exposure
- Pediatric-onset LN vs adult-onset LN
- pLNn = 46
- Outcome
- Clinical and laboratory characteristics, pLN vs aLN
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Female-to-male ratio
6.67 vs 4.82
P = 0.07
pLN
End-stage kidney disease, times more frequent
2.72
P = 0.036
person-year rate did not differ
Observational data: associations, not effects.
Original publication
Clinical and laboratory differences in pediatric-onset versus adult-onset lupus nephritis: A retrospective cohort analysis. Lupus. Published 25 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →