Comparison between UK Biobank and Shanghai Changfeng suggests distinct hip morphology may contribute to ethnic differences in the prevalence of hip osteoarthritis
Authors' conclusion
rHOA prevalence is lower in Chinese compared with White individuals. Several differences in hip shape were observed, including frequency of cam morphology, FNW, and DFH/FNW ratio.
Study context
- Population
- Participants of the UK Biobank and Shanghai Changfeng cohorts with left hip iDXA scans; mean ages 63.4 and 63.7 yearscomplete data
- Participants
- 5,924 vs 39,020
- Exposure
- Chinese Shanghai Changfeng cohort vs predominantly White UK Biobank cohort
- Shanghai Changfeng (SC)n = 5,924
- UK Biobank (UKB)n = 39,020reference
- Outcome
- Prevalence of radiographic hip OA (osteophytes grade ≥1 and joint space narrowing grade ≥1 on left hip iDXA)
Methodological detailscomparison of two cohorts, adjusted for age, height and weight, stratified by sex
- Comparison of two cohorts
- Adjusted for age, height and weight
- Stratified by sex
Main finding
As reported in the abstract
Radiographic HOA (rHOA) prevalence, females
Observational data: associations, not effects.
Further findings
rHOA prevalence, males
Cam morphology, males (rarely seen in females)
Femoral head width (composite Statistical Shape Model (SSM) modes, scaled to same size)
- SC participants had a wider femoral head compared to UKB participants
Femoral neck width (FNW), hip axis length (HAL) and diameter of femoral head (DFH)/FNW ratio
- FNW and HAL were smaller in SC compared to UKB
- DFH/FNW ratio was higher in SC
Original publication
Comparison between UK Biobank and Shanghai Changfeng suggests distinct hip morphology may contribute to ethnic differences in the prevalence of hip osteoarthritis. Osteoarthritis Cartilage. Published 5 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →