Association of Foot Symptoms With Decreased Time to All‐Cause Mortality: The Johnston County Osteoarthritis Project
Main finding · All-cause mortalityResult — go to the resultHazard ratio 1.30 95% CI 1.09–1.54Authors' conclusion
Individuals with foot symptoms had an increased hazard of all-cause mortality compared with those with no foot symptoms. These effects were independent of key confounders and were not moderated by walking speed.
Study context
- Population
- Adults aged ≥45 years in the Johnston County Osteoarthritis Project, a longitudinal population-based cohort (mean age 63 years; 65% women; 33% Black)813 deaths
- Participants
- 2,613 adults
- Exposure
- Moderate to severe foot symptoms vs no foot symptoms
- Outcome
- Time to all-cause mortality
- Follow-up
- 4 to 14.5 years
Methodological detailslongitudinal population-based cohort, Cox regression models, adjusted for potential confounders
- Longitudinal population-based cohort
- Cox regression models, adjusted for potential confounders
Main finding
All-cause mortality
Hazard ratio
1.30
95% CI 1.09–1.54
Moderate to severe foot symptomsvs No foot symptoms
HR 1.30 (95% CI 1.09–1.54)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Effect modification by walking speed or diabetes
- Association not modified by walking speed or diabetes
Prevalence of foot symptoms at baseline
- Participants with foot symptoms
- 37%
Original publication
Association of Foot Symptoms With Decreased Time to All‐Cause Mortality: The Johnston County Osteoarthritis Project. Arthritis Care Res (Hoboken). Published 3 November 2023. doi:10.
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