Spondyloarthritis & psoriatic arthritis
Clinically relevant differences in spinal mobility related to daytime performance in patients with axial spondyloarthritis
Authors' conclusion
The spinal mobility of patients with axSpA was worse in the morning but significantly improved in the afternoon. This was captured best by performance-based measures and was not seen in HC.
Study context
- Population
- Consecutive inpatients with axial spondyloarthritis (axSpA) and healthy controls
- Participants
- 100 vs 20
- Exposure
- Morning (V1: before 10:00 am) vs afternoon (V2: after 02:00 pm) assessments in axSpA, compared with healthy controls
- axSpAn = 100
- Healthy controls (HC)n = 20reference
- Outcome
- Mobility measures (BASMI, ASPI, SPPB, Epionics SPINE RoM and RoK) in the morning vs afternoon
- Follow-up
- V1: before 10:00 am; V2: after 02:00 pm
Methodological detailsconsecutive inpatients, healthy controls
- Consecutive inpatients
- Healthy controls
Main finding
As reported in the abstract
Change from morning (V1) to afternoon (V2) in axSpA
- Bath Ankylosing Spondylitis Metrology Index (BASMI), morning to afternoon
- 4.0±3.8 to 3.8±1.9; p<0.001
- ASPI, morning to afternoon (s)
- 36.2±18.3 to 28.8±11.9 s; p<0.001
- Short Physical Performance Battery (SPPB), morning to afternoon (points)
- 10.1±1.5 to 10.7±1.4 points; p<0.001
- ES speed (range of kinematics (RoK)), significant improvement
- p<0.018
- ES range of motion (RoM) lateral flexion, morning to afternoon (°)
- 13.3±7.4 to 14.7±8.2°; p=0.002
Observational data: associations, not effects.
Original publication
Clinically relevant differences in spinal mobility related to daytime performance in patients with axial spondyloarthritis. RMD Open. Published 8 January 2024. doi:10.
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