Spondyloarthritis & psoriatic arthritis

Difficult-to-treat psoriatic arthritis (D2T psoriatic arthritis (PsA)): a scoping literature review informing a GRAPPA research project

RMD OpenPublished Scoping review

Authors' conclusion

The definitions and criteria for D2T PsA and for 'active disease' are notably heterogeneous, with considerable variation across sources.

Study context

Population
Studies defining D2T PsA: PubMed (English, full text, past decade), ACR Convergence 2022, EULAR Congress 2023, Google Scholar and cited articles; search July 202315 studies from 565 references
Participants
15 studies
Outcome
Definitions and criteria of difficult-to-treat (D2T) PsA in the literature
Methodological detailsPRISMA-ScR guidelines, two independent reviewers, conflicts adjudicated by a third
  • PRISMA-ScR guidelines
  • Two independent reviewers, conflicts adjudicated by a third

Main finding

As reported in the abstract

Definitions of 'active disease' and 'resistant PsA'
  • Considerable variations in defining both 'active disease' and 'resistant PsA', most often termed 'D2T' PsA

Original publication

Difficult-to-treat psoriatic arthritis (D2T PsA): a scoping literature review informing a GRAPPA research project. RMD Open. Published 8 January 2024. doi:10.1136/rmdopen-2023-003809

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