Autoinflammatory & rare systemic diseases
Clinical profiles differ in IgG4-related disease with and without allergy: a large case-control study in China
Authors' conclusion
Allergy leads to disparities in clinical profiles in IgG4-RD patients. Allergy could result in higher relapse rate and shorten relapse-free survival time in patients receiving glucocorticoids only.
Study context
- Population
- Patients diagnosed with IgG4-related disease (IgG4-RD) at Peking University People's Hospital, China
- Participants
- 434 patients
- Comparison
- IgG4-RD with allergy vs IgG4-RD without allergy
- Outcome
- Prevalence of allergic diseases in IgG4-RD
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
With allergy
49.3%
214 events
Observational data: associations, not effects.
Further findings
- Allergy may increase relapse rate and shorten relapse-free survival time with GC only; combination of GC and immunosuppressants could improve treatment outcome
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Clinical profiles differ in IgG4-related disease with and without allergy: a large case-control study in China. Clin Exp Rheumatol. Published 19 September 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →