Spondyloarthritis & psoriatic arthritis
Clinical Characteristics and Risk Factors of Hyperkyphosis in a Chinese Cohort With Axial Spondyloarthritis: A Multicenter Retrospective Study
Study context
- Population
- Chinese patients with axial spondyloarthritis (axSpA) attending 12 hospitals across 11 centres, March 2022 to March 2024
- Participants
- 607 patients
- Outcome
- Clinical characteristics and risk factors of hyperkyphosis
Methodological detailsmulticentre, retrospective, univariate and multivariate logistic regression, nomogram model, Spearman correlation analysis
- Multicentre
- Retrospective
- Univariate and multivariate logistic regression
- Nomogram model
- Spearman correlation analysis
Main finding
As reported in the abstract
Risk factors significantly influencing hyperkyphosis (multivariate logistic regression)
- Male sex, disease duration, PGA, ESR, modified Stoke Ankylosing Spondylitis Spine Score (mSASSS), pharmacological treatment and ASDAS-CRP significantly influenced hyperkyphosis
- all P < 0.05
Observational data: associations, not effects.
Further findings
Nomogram model for clinical evaluation of hyperkyphosis
- AUC
- 0.98
- Accuracy
- 0.95
Spearman correlations between risk factors
- ASAS HI and mSASSS, positive correlation (ρ)
- 0.16, P < 0.001
- Pharmacological treatment and disease activity, negative correlation (ρ)
- −0.24, P < 0.001
- Pharmacological treatment and mSASSS, negative correlation (ρ)
- −0.18, P < 0.001
Original publication
Clinical Characteristics and Risk Factors of Hyperkyphosis in a Chinese Cohort With Axial Spondyloarthritis: A Multicenter Retrospective Study. J Rheumatol. Published 15 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →