Spondyloarthritis & psoriatic arthritis
Comparison of clinical characteristics between patients with axial spondyloarthritis with and without acute anterior uveitis: a multicentre study of the Chinese Spondyloarthritis Registry
Authors' conclusion
In Chinese patients with axSpA, older age at diagnosis, longer disease duration, presence of HLA-B27, current or past Achilles tendinitis, current or past dactylitis, current or past psoriasis, and a good response to NSAIDs were positively associated with AAU.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) in the Chinese Spondyloarthritis Registry, August 1, 2018–March 31, 2020
- Participants
- 4,304 patients
- Exposure
- axSpA with vs without acute anterior uveitis (AAU)
- Outcome
- Clinical characteristics associated with AAU
Methodological detailsobservational, multicentre, registry-based, multivariate logistic regression
- Observational
- Multicentre
- Registry-based
- Multivariate logistic regression
Main finding
As reported in the abstract
Prevalence of AAU in axSpA
Prevalence of AAU
10.59%
Observational data: associations, not effects.
Further findings
Factors associated with AAU (multivariate logistic regression)
- Age at diagnosis, OR 1.026
- P < 0.001
- Disease duration, OR 2.117
- P < 0.001
- Current or past Achilles tendinitis, OR 1.692
- P < 0.001
- Current or past dactylitis, OR 1.687
- P = 0.002
- Current or past psoriasis, OR 3.932
- P < 0.001
- Human leukocyte antigen-B27 (HLA-B27) presence, OR 2.787
- P < 0.001
- Good response to non-steroidal anti-inflammatory drugs (NSAIDs), OR 1.343
- P = 0.027
- Positive correlations
Original publication
Comparison of clinical characteristics between patients with axial spondyloarthritis with and without acute anterior uveitis: a multicentre study of the Chinese Spondyloarthritis Registry. Clin Exp Rheumatol. Published 6 October 2023. doi:10. 55563/ clinexprheumatol/ icoqy3
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