Spondyloarthritis & psoriatic arthritis
Characteristics Of Difficult-To-Treat Psoriatic Arthritis: A Comparative Analysis
Main finding · Characteristics of D2T PsA vs nD2T PsAResult — go to the resultOdds ratio 2.57 CI 1.16–5.69Authors' conclusion
D2T PsA patients had a higher prevalence of axial involvement, peripheral structural damage and therapeutic discontinuation due to poor dermatological control whereas Very D2T PsA patients were more likely obese with axial involvement. Very D2T PsA represent a minim proportion among patients when applying a more stringent definition.
Study context
- Population
- Psoriatic arthritis (PsA) patients at a tertiary center, included 2004 to 2015
- Participants
- 49 / 17 / 101
- Exposure
- D2T PsA and Very D2T PsA vs nD2T PsA
- D2T PsAn = 49
- Very D2T PsAn = 17
- nD2T PsAn = 101reference
- Outcome
- Characteristics of D2T PsA patients using the EULAR definition
Methodological detailssingle-centre, tertiary center
- Single-centre
- Tertiary center
Main finding
Characteristics of D2T PsA vs nD2T PsA · baseline
Odds ratio
2.57
CI 1.16–5.69
P = 0.020
D2T PsAvs nD2T PsA
OR 2.57 (CI 1.16–5.69); P = 0.020
As reported in the abstract
- Higher prevalence of axial involvement in D2T PsA
- P = 0.030
- Higher prevalence of axial and/or peripheral structural damage at baseline in D2T PsA
- P = 0.007
- More bDMARD discontinuation due to poor dermatological control in D2T PsA
- P = 0.005
Observational data: associations, not effects.
Further findings
- Very D2T PsA (more stringent definition with temporal criterion) vs nD2T PsA — Very D2T PsA
- 11.3%
- Very D2T PsA (more stringent definition with temporal criterion) vs nD2T PsA — Higher proportion of obesity in Very D2T PsA
- p=0.015
- Very D2T PsA (more stringent definition with temporal criterion) vs nD2T PsA — Axial involvement more prevalent in Very D2T PsA
- p=0.020
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Characteristics Of Difficult-To-Treat Psoriatic Arthritis: A Comparative Analysis. Semin Arthritis Rheum. Published 5 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →