Spondyloarthritis & psoriatic arthritis
Characteristics of difficult-to-treat axial spondyloarthritis: Results of a real-world multicentric study
Authors' conclusion
D2T axSpA was associated with higher disease activity, peripheral involvement, extra-musculoskeletal manifestations and fibromyalgia.
Study context
- Population
- Patients with axSpA, multicentric real-world cohort
- Participants
- 88 / 12 / 223
- Exposure
- D2T axSpA and Very D2T axSpA vs non-D2T axSpA
- D2Tn = 88
- Very D2Tn = 12
- Non-D2T (nD2T)n = 223reference
- Outcome
- Characteristics of D2T vs nD2T axSpA
Methodological detailsmulticentre, real-world
- Multicentre
- Real-world
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | D2T | Very D2T | nD2T | P value |
|---|---|---|---|---|
| Peripheral involvementD2T vs nD2T | 34.9% | — not stated in the abstract | 21.4% | P = 0.015 |
| BASDAI at baselineD2T vs nD2T | 63.7 ± 16.5 | — not stated in the abstract | 58.8 ± 14.7 | P = 0.015 |
| Proportion Very D2T | — not stated in the abstract | 3.8% | — not stated in the abstract | |
| CRP at baselineVery D2T vs nD2T | — not stated in the abstract | 42.0 ± 31.3 | 17.8 ± 23.1 | P = 0.010 |
| IBD prevalence at baselineVery D2T vs nD2T | — not stated in the abstract | 41.7% | 3.1% | P < 0.001 |
| FM in Very D2T | — not stated in the abstract | 0 events | — not stated in the abstract |
— not stated in the abstract
- FM · D2T vs nD2T
- P < 0.001
FM
- FM more frequent in D2T vs nD2T
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Characteristics of difficult-to-treat axial spondyloarthritis: Results of a real-world multicentric study. Joint Bone Spine. Published 29 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →