Spondyloarthritis & psoriatic arthritis

Assessment of axial spondyloarthritis activity using a magnetic resonance imaging-based multi-region-of-interest fusion model

Arthritis Res TherPublished Retrospective diagnostic accuracy study

Authors' conclusion

The multi-ROI fusion radiomics model developed in this study differentiated between active and non-active axSpA using sacroiliac FS T2w-MRI.

Study context

Population
Patients diagnosed with axial spondyloarthritis (axSpA); Fat-suppressed (FS) T2-weighted (T2w) magnetic resonance imaging (MRI) of sacroiliac joints
Participants
109 patients
Comparison
MRI radiomics fusion model for active vs non-active axSpA
  • Non-active axSpAn = 68
  • Active axSpAn = 41
Outcome
Differentiation of active from non-active axSpA by radiomics model (accuracy, sensitivity, specificity)
Methodological detailsradiomics, training and testing cohorts (8:2), 3.0 T sacroiliac MRI, multi-ROI fusion model
  • Radiomics
  • Training and testing cohorts (8:2)
  • 3.0 T sacroiliac MRI
  • multi-ROI fusion model

Performance

As reported in the abstract

Fusion ROI model performance, training vs testing cohort

Accuracy (training vs testing)

0.90 vs.0.81

Sensitivity (training vs testing)

0.90 vs. 0.75

Specificity (training vs testing)

0.90 vs. 0.85

Further findings

Radiomics features extracted (Circle- and Facet-based models)

Features extracted
2284

Original publication

Assessment of axial spondyloarthritis activity using a magnetic resonance imaging-based multi-region-of-interest fusion model. Arthritis Res Ther. Published 24 November 2023. doi:10.1186/s13075-023-03193-6

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