Chronic neck pain is associated with increased mortality in individuals with osteoarthritis: results from the NHANES database prospective cohort study
Authors' conclusion
Neck pain was strongly associated with osteoarthritis. Moreover, chronic neck pain over 1 year significantly increased the mortality of OA patients.
Study context
- Population
- Participants of the US National Health and Nutrition Examination Survey (NHANES); Osteoarthritis (OA) patients for mortality analysis
- Participants
- 5,965 participants
- Exposure
- Neck pain vs no neck pain
- Outcome
- Association of neck pain with OA prevalence and with all-cause mortality in OA patients
Methodological detailsNHANES database, linkage to National Death Index, multivariable logistic regression, Cox proportional hazards models
- NHANES database
- Linkage to National Death Index
- Multivariable logistic regression
- Cox proportional hazards models
Main finding
As reported in the abstract
All-cause mortality in OA patients, chronic neck pain (over 1 year)
Unadjusted
2.94
CI 1.61–5.37P < 0.01
Adjusted
3.30
CI 1.23–45.85P < 0.05
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | P value |
|---|---|---|
| Association of neck pain with OANeck pain vs No neck pain · unadjusted | 1.932 (CI 1.232–3.028) | P < 0.01 |
| Association of neck pain with OANeck pain vs No neck pain | 2.519 (CI 1.325–4.788) | P < 0.01 |
- Association of neck pain with OA: adjusted; significant also in stratified analysis by sex, race and smoke status
Prevalence among all participants
- OA
- 8.18%
- Neck pain
- 5.92%
Original publication
Chronic neck pain is associated with increased mortality in individuals with osteoarthritis: results from the NHANES database prospective cohort study. Arthritis Res Ther. Published 19 July 2023. doi:10.
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