Lupus & antiphospholipid syndrome
Cardiovascular magnetic resonance as an initial screening tool in individuals with SLE and chest pain
Authors' conclusion
This cross-sectional study highlights cardiac ischaemia as a cause of chest symptoms in SLE. Notably, CAD and CMD were together more common than pericarditis and myocarditis.
Study context
- Population
- Adults with SLE reporting chest pain or dyspnoea suggestive of cardiac involvement to a rheumatologist, 2018–202384% female
- Participants
- 19 adults
- Outcome
- CAD, CMD, pericarditis and myocarditis identified by CMR
Methodological details14 (74%) examined using adenosine stress
- 14 (74%) examined using adenosine stress
Main finding
As reported in the abstract
Diagnoses identified by CMR
- Coronary artery disease (CAD) (of 14 with adenosine stress)
- 3/14 (21%)
- Coronary microvascular dysfunction (CMD) (of 14 with adenosine stress)
- 2/14 (14%)
- Pericarditis
- 3/19 (16%)
- Myocarditis
- 0
- No cause of chest symptoms revealed
- 12/19 (63%)
Observational data: associations, not effects.
Further findings
Cardiovascular magnetic resonance (CMR) results led to altered medical management
- Altered medical management
- 6/19 (32%)
Original publication
Cardiovascular magnetic resonance as an initial screening tool in individuals with SLE and chest pain. Lupus Sci Med. Published 10 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →