Lupus & antiphospholipid syndrome

Advanced imaging in the evaluation of lupus arthritis: A systematic literature review and meta-analysis

Semin Arthritis RheumPublished Systematic review and meta-analysis

Authors' conclusion

The current systematic literature review examined available information on the use of advanced imaging modalities in the evaluation of hand and wrist involvement in SLE.

Study context

Population
Patients with SLE hand and wrist arthritis
Participants
16 / 8 / 1
Comparison
Musculoskeletal (MSK) ultrasound (US) vs magnetic resonance imaging (MRI) vs optical imaging (OI)
  • MSK USn = 16
  • MRIn = 8
  • OIn = 1
Outcome
Pooled association with US synovitis and tenosynovitis
Methodological detailsPopulation, intervention, comparator, and outcome structured (PICOS)-structured literature searches, PubMed, EMBASE and Cochrane Library
  • PICOS-structured literature searches
  • PubMed, EMBASE and Cochrane Library

Pooled result

As reported in the abstract

Arthritis/arthralgia and US synovitis

10.89

4.02, 29.48

Arthritis/arthralgia and US tenosynovitis

5.93

1.99, 17.72

Joint symptoms and US synovitis, restricted to physician confirmed arthritis

5.00

1.11, 22.60

Original publication

Advanced imaging in the evaluation of lupus arthritis: A systematic literature review and meta-analysis. Semin Arthritis Rheum. Published 14 February 2025. doi:10.1016/j.semarthrit.2025.152661

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