Cardiovascular health metrics and all-cause mortality in osteoarthritis, inflammatory arthritis, and unclassified arthritis patients: a national prospective cohort study
Authors' conclusion
Ideal CVH substantially decreases all-cause mortality risk among patients with arthritis, confirming the critical role of CVH in arthritis management.
Study context
- Population
- Patients with arthritis in the United States, National Health and Nutrition Examination Survey
- Participants
- 5,919 patients
- Exposure
- Higher vs lower cardiovascular health (CVH) scores
- Outcome
- All-cause mortality
Methodological detailsnational, Cox proportional hazard regression, restricted cubic spline analysis
- National
- Cox proportional hazard regression
- Restricted cubic spline analysis
Main finding
As reported in the abstract
All-cause mortality per 10-point increment in CVH score
Estimate (95% CI)P value
Each 10-point CVH increment
HR (unadjusted) 0.77(0.71–0.83)
P < 0.001Each 10-point CVH increment
HR (adjusted for age, sex, race, social determinants of health) 0.72(0.67–0.79)
P < 0.001Each 10-point CVH increment, as printed
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| All-cause mortality, idealvs lower CVH at baseline | 0.39 (0.26–0.59) | P < 0.001 | |
| 0.20.5125Hazard ratio (log scale) |
CVH and all-cause mortality by arthritis type (subgroups)
- Similar results not observed in inflammatory arthritis, but seen in osteoarthritis or degenerative arthritis, and unknown types of arthritis
Original publication
Cardiovascular health metrics and all-cause mortality in osteoarthritis, inflammatory arthritis, and unclassified arthritis patients: a national prospective cohort study. Arthritis Res Ther. Published 16 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →