Vasculitis & polymyalgia rheumatica
Behçet's syndrome incidence and prevalence in Sardinia: implications of a latent class analysis combining administrative and clinical data
Authors' conclusion
BS in Sardinia is a rare disease.
Study context
- Population
- Cases with a diagnosis of Behçet's syndrome (BS) in Sardinia, from Hospital Discharge Records (HDRs) and Rare Diseases Regional Register (RDRR) (2006–2016), Specialist Outpatient Database (SOD) (2014–2016) and regional rheumatology clinic records193 confirmed BS cases
- Participants
- 280 participants
- Outcome
- Prevalence and incidence of BS in Sardinia
Methodological detailslatent class analysis, combined administrative and clinical data
- Latent class analysis
- Combined administrative and clinical data
Main finding
As reported in the abstract
BS prevalence (ICBD, LCA) · 2016
- Prevalence per 100,000 inhabitants
- 11.7
- Prevalence per 100,000, women
- 15.7
- Prevalence per 100,000, men
- 7.6
- Annual incidence per 100,000 inhabitants (2014-2016)
- 0.24 to 0.48
- Confirmed BS cases by latent class analysis (LCA)
- 193 (68.9%)
Observational data: associations, not effects.
Further findings
Prevalence and incidence using International Study Group (ISG) criteria
- Lower than with International Criteria for Behçet's Disease (ICBD)
Database sensitivity and specificity
- Sensitivity
- 40.6% to 70.5%
- Specificity
- 16.3% to 99.0%
Original publication
Behçet's syndrome incidence and prevalence in Sardinia: implications of a latent class analysis combining administrative and clinical data. Clin Exp Rheumatol. Published 19 September 2025. doi:10.
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