Vasculitis & polymyalgia rheumatica
Behçet's disease and pregnancy: retrospective study and updated review of the literature
Authors' conclusion
Our findings suggest that Behçet's disease does not usually worsen during pregnancy and that favourable pregnancy outcomes are achievable. Nonetheless, the risk of complications, although relatively low, supports the need for preconception counselling and close multidisciplinary monitoring. This study contributes new insights from a specialised referral centre to the limited body of evidence available on this topic.
Study context
- Population
- Patients with a confirmed diagnosis of behçet's disease (BD) followed at the outpatient clinics of Policlinico Umberto I, Rome, Italypatients with a total of 48 pregnancies
- Participants
- 25 patients
- Outcome
- Disease activity during pregnancy
Methodological detailsliterature review
- Literature review
Main finding
As reported in the abstract
Remained stable
80% of cases
Observational data: associations, not effects.
Further findings
- Overall live birth rate
- 89.58%
Safety
Pregnancy complications
- Pregnancies with complications
- 13 pregnancies (27.08%)
- Mostly in pregnancies that occurred before BD diagnosis
- 21%
- Most common: spontaneous miscarriage and deep vein thrombosis
- Each in one case: threatened miscarriage, preterm delivery, low birth weight, gestational diabetes, gestational hypertension, premature rupture of membranes
Original publication
Behçet's disease and pregnancy: retrospective study and updated review of the literature. Clin Exp Rheumatol. Published 26 October 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →