Bariatric surgery, osteoarthritis and arthroplasty of the hip and knee in Swedish Obese Subjects – up to 31 years follow-up of a controlled intervention study
Main finding · Hip OA, incidence rateResult — go to the resultAdjusted hazard ratio 0.83 95% CI 0.69–1.00Authors' conclusion
Bariatric surgery did not normalize the increased risk of knee and hip osteoarthritis in patients with obesity but was associated with an increased incidence of knee arthroplasty compared to the control group.
Study context
- Population
- Patients with obesity in the Swedish Obese Subjects (SOS) study, plus a general-population reference cohort
- Participants
- 2,007 / 2,040 / 1,135
- Exposure
- Bariatric surgery vs matched controls given usual obesity care; general-population reference cohort
- Surgeryn = 2,007
- Controlsn = 2,040reference
- Referencen = 1,135
- Outcome
- Incidences of OA and arthroplasty of hip and knee (HR and IR)
Methodological detailsnon-randomized, matched controls, Median follow-up 21.2 (IQR 16.4-24.8) years controls, 22.9 (IQR 19.1-25.7) surgery, 20.1 (IQR 18.7-20.9) reference cohort
- Non-randomized
- Matched controls
- Median follow-up 21.2 (IQR 16.4-24.8) years controls, 22.9 (IQR 19.1-25.7) surgery, 20.1 (IQR 18.7-20.9) reference cohort
Main finding
Hip OA, incidence rate
Adjusted hazard ratio
0.83
95% CI 0.69–1.00
By group
Surgery
5.3
Incidence rates (IR) · 95% CI 4.7–6.1
Controls
6.6
IR · 95% CI 5.9–7.5
Surgeryvs Controls
adjHR 0.83 (95% CI 0.69–1.00)
As reported in the abstract
Observational data: associations, not effects.
Further findings
IR
| Outcome | Surgery | Controls | adjHR (95% CI) | |
|---|---|---|---|---|
| Knee arthroplasty, incidence rateSurgeryvs Controls | 7.4 (95% CI 6.6–8.2) | 5.6 (95% CI 4.9–6.4) | 1.45 (1.22–1.74) | |
| 0.512Adjusted hazard ratio (log scale) |
Hip arthroplasty
- Similar incidence in surgery group and controls
Knee OA
- Similar incidence in surgery group and controls
OA and arthroplasty of hip and knee, reference cohort
- Lower incidences in reference cohort vs surgery group and controls
Original publication
Bariatric surgery, osteoarthritis and arthroplasty of the hip and knee in Swedish Obese Subjects – up to 31 years follow-up of a controlled intervention study. Osteoarthritis Cartilage. Published 6 February 2023. doi:10.
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