Systemic sclerosis & Raynaud's
Autonomic dysfunction in systemic sclerosis: A scoping review
Authors' conclusion
A strong influence of ANS deregulation on SSc clearly emerges from the literature.
Study context
- Population
- Systemic sclerosis (SSc) patients; original data on autonomic nervous system involvement (pathogenesis, clinical presentation, diagnostic tools)
- Participants
- 2,742 patients109 studies
- Outcome
- Dysautonomia in SSc
Methodological detailsliterature search of MEDLINE and Web of Science
- Literature search of MEDLINE and Web of Science
Main finding
As reported in the abstract
- Cardiovascular system most extensively investigated (heart rate variability with 24 h Holter ECG or Ewing's autonomic tests)
- Important signs of dysautonomia also found in digital vasculopathy, gastrointestinal system and SSc skin, assessed with non-invasive techniques and histologically
- 467 papers identified
Original publication
Autonomic dysfunction in systemic sclerosis: A scoping review. Semin Arthritis Rheum. Published 26 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →