Associations between pain sensitization and measures of physical function in people with hand osteoarthritis: Results from the Nor-Hand study
Main finding · AUSCAN function (0-36) per SD of PPTResult — go to the resultbeta −1.41 95% CI −2.40 to −0.42Authors' conclusion
Peripheral sensitization, and possibly central sensitization, was associated with impaired function.
Study context
- Population
- People with hand osteoarthritis (OA) in the Nor-Hand study
- Participants
- 206 people
- Exposure
- Pain sensitization vs measures of hand and lower extremity function
- Outcome
- Hand function (AUSCAN 0-36, grip strength, Moberg pick-up test) and lower extremity function (WOMAC 0-68, 30-s chair stand test, 40-m walk test)
Methodological detailslinear regression, causal-inference based mediation analysis
- Linear regression
- Causal-inference based mediation analysis
Main finding
AUSCAN function (0-36) per SD of PPT
beta
−1.41
95% CI −2.40 to −0.42
As reported in the abstract
Observational data: associations, not effects.
Original publication
Associations between pain sensitization and measures of physical function in people with hand osteoarthritis: Results from the Nor-Hand study. Osteoarthritis Cartilage. Published 24 July 2023. doi:10.
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