Associations between quantitative sensory tests and measures of pain and function in persons over 45 with meniscal tear
Authors' conclusion
In this cross-sectional assessment of individuals with meniscal tear and OA, associations between QST measures and measures of pain, strength and performance were generally weak, suggesting pain sensitization makes minor contributions to these objective and subjective outcomes.
Study context
- Population
- Participants in the TeMPO trial of nonoperative therapies for meniscal tear and osteoarthritis (OA); mean age 59.1 years, 58% female
- Participants
- 317 participants
- Exposure
- Lowest vs highest tercile of each quantitative sensory testing (QST) measure
- Outcome
- Associations between QST measures (PPT, TS, CPM) and pain, muscle strength and performance measures
Methodological detailssecondary analysis of the TeMPO trial, linear regression adjusted for age, body mass index (BMI) and Kellgren-Lawrence (KL) grade
- Secondary analysis of the TeMPO trial
- Linear regression adjusted for age, BMI and KL grade
Main finding
As reported in the abstract
Correlations between QST measures and outcomes
generally < 0.20
Adjusted SMD in each outcome, lowest vs highest tercile of each QST measure
generally differed by <0.30 SD
Observational data: associations, not effects.
Original publication
Associations between quantitative sensory tests and measures of pain and function in persons over 45 with meniscal tear. Osteoarthritis Cartilage. Published 20 February 2026. doi:10. 1016/ j. joca. 2026. 02. 006
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