Lupus & antiphospholipid syndrome
Association of Patient Resilience With Patient-Reported Physical and Mental/Emotional Quality of Life in Systemic Lupus Erythematosus
Authors' conclusion
High patient resilience was independently associated with better HRQOL outcomes in SLE after adjusting for demographics, SDOH, SLE flare, site, time, and comorbid rheumatic diseases.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE) at 15 rheumatology clinics across the US who viewed a patient decision aid for SLE management during a regular clinic visit27% high resilience
- Participants
- 945 patients
- Exposure
- High vs low patient resilience
- Outcome
- HRQOL on Patient Reported Outcomes Measurement Information System (PROMIS-29) domains
Methodological detailsmulticentre, multivariable linear mixed-effects model
- Multicentre
- Multivariable linear mixed-effects model
Main finding
As reported in the abstract
HRQOL (PROMIS-29 domains)
Unadjusted: small favorable effect size for sleep disturbance
Cohen d 0.2-0.49
Observational data: associations, not effects.
Further findings
Excellent or very good health
| Outcome | High resilience | Low resilience |
|---|---|---|
| SLE activity (0-10 scale) | 3.94 0-10 scale | 5.18 0-10 scale |
| SLE wellness (0-10 scale) | 7.54 0-10 scale | 6.15 0-10 scale |
Original publication
Association of Patient Resilience With Patient-Reported Physical and Mental/Emotional Quality of Life in Systemic Lupus Erythematosus. J Rheumatol. Published 15 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →