Osteoarthritis

Association of Changes in Hand Pain With Body Mass Index (BMI), Employment, and Mental Well‐Being Over Four Years in Patients With Hand Osteoarthritis

Arthritis Care Res (Hoboken)Published Prospective cohort study

Authors' conclusion

The pain course of patients with hand OA is variable, not inevitably worsening, and various factors may play a role.

Study context

Population
Patients with hand osteoarthritis (OA), Hand OSTeoArthritis in Secondary Care cohort (83% female, mean age 60.6 years, mean AUSCAN pain 9.1)analysed
Participants
356 patients
Outcome
Change in AUSCAN pain (0-20): deterioration, stable or improvement by Minimal Clinical Important Improvement; good clinical outcome by PASS
Follow-up
4 years
Methodological details4-year annual follow-up, multinomial or binary logistic regression adjusted for baseline pain, age, sex and BMI
  • 4-year annual follow-up
  • Multinomial or binary logistic regression adjusted for baseline pain, age, sex and BMI

Main finding

As reported in the abstract

Hand pain course (AUSCAN pain)

Pain improved

38%

Pain deteriorated

30%

Pain remained stable

32%

Observational data: associations, not effects.

Further findings

Patient Acceptable Symptom State (PASS) reached

At baseline
44%
At follow-up
49%

Baseline factors associated with pain change

Higher BMI, coping through comforting cognitions and illness comprehension positively associated with pain deterioration
Higher AUSCAN function score, mental well-being and illness consequences negatively associated with pain improvement
Employment (positive) and emotional representations (negative) associated with both improvement and deterioration

Baseline factors associated with PASS after 4 years

Higher baseline AUSCAN function, tender joint count and symptoms attributed to hand OA negatively associated with PASS

Original publication

Association of Changes in Hand Pain With BMI, Employment, and Mental Well‐Being Over Four Years in Patients With Hand Osteoarthritis. Arthritis Care Res (Hoboken). Published 27 January 2025. doi:10.1002/acr.25480

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