Lupus & antiphospholipid syndrome
Assessment of subclinical cardiovascular risk in systemic lupus erythematosus utilizing carotid ultrasound and clinical evaluation
Authors' conclusion
Carotid ultrasound was associated with in the subclinical detection of CVR in this cohort, providing complementary data to clinical evaluations.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE) undergoing carotid US with Framingham and QRISK-3 cardiovascular risk (CVR) scores and SLEDAI
- Participants
- 37 patients
- Outcome
- Correlation of CVR clinical scores with carotid US findings, clinical and laboratory variables
Main finding
As reported in the abstract
Correlations of Framingham score, QRISK-3 and carotid artery diameter with QIMT RF and expected values
Correlation coefficients (statistically significant)
0.45 to 0.84
P values
0.01 to <0.01
Observational data: associations, not effects.
Further findings
Linear regression: variables influencing expected QIMT
- QRISK-3, age, statin use and diabetes mellitus; P values
- 0.034 to <0.001
Linear regression: variables influencing QIMT RF
- Age and Framingham score; P values
- 0.028 to 0.004
SLEDAI and US parameters
- SLEDAI did not significantly impact ultrasonographic parameters
Original publication
Assessment of subclinical cardiovascular risk in systemic lupus erythematosus utilizing carotid ultrasound and clinical evaluation. Lupus. Published 20 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →