Lupus & antiphospholipid syndrome

Alignment of contraception use with the American College of Rheumatology (ACR) reproductive health guidelines in women with systemic lupus erythematosus within the Rheumatology Informatics System for Effectiveness (RISE) registry

Lupus Sci MedPublished Retrospective cohort study

Authors' conclusion

Practices participating in the RISE registry do not currently record contraception in the large majority of women with SLE, although increased documentation in some EHRs suggests that system changes may improve rates of documentation.

Study context

Population
Female patients (aged 18–44 years) with SLE in the RISE registry, rheumatology clinics across the USA
Exposure
Prepandemic vs mid-pandemic; contraception patterns compared with the 2020 ACR guidelines
Outcome
Contraception documentation and its predictors; alignment of contraception practices with the 2020 ACR guidelines
Methodological detailsregistry-based, multicentre, adjusted multilevel logistic modelling
  • Registry-based
  • Multicentre
  • Adjusted multilevel logistic modelling

Main finding

As reported in the abstract

Contraception documentation rate

Observational data: associations, not effects.

Further findings

With thrombotic risk vs Without thrombotic risk

Oestrogen-containing contraceptive prescription by thrombotic risk

P < 0.0001

With history of lupus nephritis (LN) vs Without history of LN

Oestrogen-containing contraceptive prescription by history of LN

P = 0.024

Original publication

Alignment of contraception use with the ACR reproductive health guidelines in women with systemic lupus erythematosus within the RISE registry. Lupus Sci Med. Published 24 August 2024. doi:10.1136/lupus-2024-001192

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