Lupus & antiphospholipid syndrome
Clinical significance of serum soluble scavenger receptor CD163 in patients with lupus nephritis
Authors' conclusion
Serum sCD163 was elevated in LN patients than in SLE patients, which could be used to predict the occurrence and prognosis of LN.
Study context
- Population
- Systemic lupus erythematosus (SLE) and lupus nephritis (LN) patients classified according to standard identification criteria
- Comparison
- Serum soluble CD163 (sCD163) in LN vs SLE patients
- Outcome
- Whether serum sCD163 could predict the occurrence and prognosis of LN
Methodological detailsROC analysis, Spearman correlation analysis
- ROC analysis
- Spearman correlation analysis
Performance
As reported in the abstract
Serum sCD163 and LN
- sCD163 was elevated in LN patients and could be used to diagnose LN
Further findings
sCD163 and SLE disease activity index in LN
- sCD163 was increased in LN patients with a heavy SLE disease activity index
sCD163 and treatment response (prognosis of LN)
- sCD163 higher in LN patients with no response than with complete or partial response; could predict prognosis of LN
Risk factors correlated to LN (11 indices)
- Six positive indices and one negative risk factor correlated to LN
Original publication
Clinical significance of serum soluble scavenger receptor CD163 in patients with lupus nephritis. Lupus. Published 22 August 2024. doi:10.
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