Lupus & antiphospholipid syndrome
Age-Stratified 30-day Rehospitalization and Mortality and Predictors of Rehospitalization Among Patients With Systemic Lupus Erythematosus: A Medicare Cohort Study
Authors' conclusion
Young adults with SLE on Medicare had very high 30-day rehospitalization at 36%. Considering socioeconomic disadvantage and comorbidities provided good prediction of rehospitalization risk, particularly in young adults.
Study context
- Population
- Medicare beneficiaries hospitalized in 2014 (20% national sample), with and without systemic lupus erythematosus (SLE)
- Participants
- 1.39 million hospitalizations
- Exposure
- SLE vs no SLE, by age group
- Outcome
- Rehospitalization risk and mortality within 30 days of discharge, by age group
- Follow-up
- 30 days after discharge
Methodological details2014 20% national Medicare sample, multivariable generalized estimating equation models
- 2014 20% national Medicare sample
- Multivariable generalized estimating equation models
Main finding
As reported in the abstract
30-day rehospitalization · 30 days
Young SLE
36%
- Young SLE vs young peers without SLE: rehospitalization higher
- 40%
- Young SLE vs older SLE: rehospitalization higher
- 85%
Observational data: associations, not effects.
Further findings
Predictors of rehospitalization in SLE
- Model predictive value (C statistics)
- 0.67-0.77
- Longer LOS and higher comorbidity risk score increased odds of rehospitalization in all age groups; specific comorbid predictors varied
- Models incorporated neighborhood-level socioeconomic disadvantage
Original publication
Age-Stratified 30-day Rehospitalization and Mortality and Predictors of Rehospitalization Among Patients With Systemic Lupus Erythematosus: A Medicare Cohort Study. J Rheumatol. Published 15 August 2022. doi:10.
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