Lupus & antiphospholipid syndrome

Associations of retention in care by visits or lupus-specific labs with acute care among young adults: A medicare cohort study

LupusPublished Retrospective cohort study

Main finding · Acute care use, adjustedResult — go to the resultAdjusted hazard ratio 0.79 95% CI 0.65–0.97

Authors' conclusion

Receipt of complement or dsDNA antibody testing, a lupus-specific care quality indicator, was associated with reduced acute care use in young adults.

Study context

Population
Young adult (ages 18–35) Medicare beneficiaries with SLE28% had serologic testing
Participants
1,036 participants
Exposure
Visit-based retention in rheumatology care or receipt of ≥1 complement or dsDNA test vs none
Outcome
Acute care use (ED visits and hospitalizations)
Follow-up
Subsequent 6 months
Methodological details20% national Medicare sample, Cox regression
  • 20% national Medicare sample
  • Cox regression

Main finding

Acute care use, adjusted · 6 months

Adjusted hazard ratio

0.79

95% CI 0.65–0.97

Serologic testingvs No serologic testing
aHR 0.79 (95% CI 0.65–0.97)

As reported in the abstract

Acute care use at 6 months (overall)
nearly 60%

Observational data: associations, not effects.

Further findings

Observed acute care-free survival time — Visit-based retention vs No visit-based retention

P = 0.02

OutcomeP value
Observed acute care-free survival timeSerologic testing vs No serologic testingP = 0.002

Original publication

Associations of retention in care by visits or lupus-specific labs with acute care among young adults: A medicare cohort study. Lupus. Published 18 July 2025. doi:10.1177/09612033251360289

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