Vasculitis & polymyalgia rheumatica
Visual manifestations in giant cell arteritis: identification of risk factors from the ARTESER Registry
Authors' conclusion
One-third of GCA patients present visual manifestations at diagnosis. Older age and jaw claudication are independent predictors of visual manifestations, whereas polymyalgia rheumatica, fever, longer symptom duration and high ESR reduce the risk of visual involvement.
Study context
- Population
- Patients with GCA diagnosed between June 2013 and March 2019, ARTESER Spanish multicentre registry
- Participants
- 1,636 patients
- Exposure
- GCA patients with vs without visual involvement
- With visual involvementn = 599
- Outcome
- Prevalence and predictive factors of visual manifestations at diagnosis
- Follow-up
- At diagnosis
Methodological detailsmulticentre, registry, multivariate logistic regression
- Multicentre
- Registry
- Multivariate logistic regression
Main finding
As reported in the abstract
Visual manifestations: prevalence and independent predictors (OR)
Visual manifestations
36.6%
599 events
- Older age, OR
- 1.027; 1.009-1.045 (95% CI)
- Jaw claudication, OR
- 1.724; 1.325-2.243 (95% CI)
- PMR, OR
- 0.541; 0.414-0.708 (95% CI)
- Fever, OR
- 0.373; 0.264-0.527 (95% CI)
- Longer symptom duration, OR
- 0.946; 0.909-0.985 (95% CI)
- Higher erythrocyte sedimentation rate (ESR), OR
- 0.992; 0.988-0.997 (95% CI)
Observational data: associations, not effects.
Further findings
Anterior ischemic optic neuropathy among patients with visual manifestations
- Most frequent ocular complication (n of patients with visual manifestations; %)
- 274 of 599; 45.7%
Original publication
Visual manifestations in giant cell arteritis: identification of risk factors from the ARTESER Registry. Rheumatology (Oxford). Published 20 January 2024. doi:10.
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