Vasculitis & polymyalgia rheumatica

Incidence and clinical manifestations of giant cell arteritis in Spain: results of the ARTESER register

RMD OpenPublished Multicentre register-based incidence study

Authors' conclusion

We found a predominance among women and during the ninth decade of life with no clear variability according to geographical area or seasons of the year.

Study context

Population
Patients aged ≥50 years diagnosed with giant cell arteritis (GCA) between 1 June 2013 and 29 March 2019 at 26 hospitals of the Spanish National Health System (positive biopsy or imaging, 3/5 1990 ACR criteria, or expert clinical diagnosis)cases of GCA
Participants
1,675 patients
Comparison
Women vs Men
Outcome
Annual incidence of GCA per 100 000 people ≥50 years
Methodological details26 hospitals of the National Health System, Poisson regression
  • 26 hospitals of the National Health System
  • Poisson regression

Main finding

As reported in the abstract

Annual incidence of GCA (cases per 100 000 people ≥50 years)

Annual incidence, overall

7.42

95% CI 6.57 to 8.27

Further findings

Incidence by sex (cases per 100 000 people ≥50 years)

Incidence by sex (cases per 100 000 people ≥50 years)

Incidence greater in women than in men

Peak incidence, age 80-84 years (cases per 100 000)

Incidence at age 80-84 years
23.06 (95% CI 20.89 to 25.4)

Geographical distribution and seasonal incidence

No significant differences between geographical distribution and incidence throughout the year (p=0.125)

Phenotype at diagnosis (patients)

Cranial
1091
Extracranial
337
Mixed
170

Age at diagnosis

Mean age at diagnosis, years (±8.3)
76.9

Original publication

Incidence and clinical manifestations of giant cell arteritis in Spain: results of the ARTESER register. RMD Open. Published 26 March 2024. doi:10.1136/rmdopen-2023-003824

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