Lupus & antiphospholipid syndrome
Visceral fat, cardiovascular risk factors and quality of life in lupus activity categorised via complement C3
Authors' conclusion
Inactive patients with SLE exhibited more adverse cardiovascular risk markers compared with active patients categorised by complement C3, even when glucocorticoid administration was accounted for.
Study context
- Population
- Patients with SLE stratified by complement C3, and controls with obesity-related low-grade inflammation, Hospital Universitario Puerta de Hierro Majadahonda
- Participants
- 74 SLE patients
- Exposure
- Inactive SLE (C3 >90 mg/dL) vs active SLE (C3 <90 mg/dL), alongside controls with obesity-related low-grade inflammation
- Controlsn = 74
- Outcome
- Adiposity profile
Methodological detailssingle-centre, regression models adjusted for variables associated with disease activity
- Single-centre
- Regression models adjusted for variables associated with disease activity
Main finding
As reported in the abstract
| Group | Value | Visceral fat mass |
|---|---|---|
| Inactive SLE | 36.7% total fat mass | 8.5 AU |
| Active SLE | 33.2% total fat mass | 6.5 AU |
Value
Inactive SLE36.7% total fat mass
Active SLE33.2% total fat mass
Visceral fat mass
Inactive SLE8.5 AU
Active SLE6.5 AU
Observational data: associations, not effects.
Original publication
Visceral fat, cardiovascular risk factors and quality of life in lupus activity categorised via complement C3. Lupus Sci Med. Published 14 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →