Fibromyalgia & musculoskeletal pain
Via Dolorosa: impact of nociplastic pain on hospitalisation outcomes. A retrospective cohort study
Authors' conclusion
Nociplastic pain diagnoses are associated with prolonged hospitalisations, increased readmissions, and OUD, but lower long-term mortality.
Study context
- Population
- Hospitalised adults (≥18 years), hospital records
- Participants
- 18,393 adults
- Exposure
- Nociplastic pain vs hospitalised patients without these diagnoses
- Researchn = 3,326
Methodological detailsadjusted for age and sex
- Adjusted for age and sex
Further findings
LOS, index hospitalisation (adjusted)
P = 0.002
| Outcome | HR | P value |
|---|---|---|
| 5-year mortality | 0.523 | P < 0.001 |
- Recurrent hospitalisations within 6 months (adjusted)
- P < 0.001
- Opioid use disorder (adjusted) — Share of Opioid use disorder (OUD) cases in the research group
- 87.5% · P < 0.001
Recurrent hospitalisations within 6 months (adjusted)
- Higher recurrent hospitalisations in the research group
Original publication
Via Dolorosa: impact of nociplastic pain on hospitalisation outcomes. A retrospective cohort study. Clin Exp Rheumatol. Published 3 November 2025. doi:10.
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