Fibromyalgia & musculoskeletal pain
Platelet-rich plasma versus corticosteroids in facet joint syndrome: A controlled, randomized, double-blind study
Authors' conclusion
In patients with facet joint syndrome, PRP injections did not demonstrate superiority over CTC injections in terms of pain relief or clinically significant functional improvement at 6months.
Study context
- Population
- Patients with facet joint syndrome
- Participants
- 76 patients
- Comparison
- Intra-articular PRP injections vs corticosteroid (CTC) injections into painful facet joints
- Primary endpoint
- 50% improvement in NRS (0-10) for spontaneous lumbar pain
- Follow-up
- 6 months
Methodological detailssuperiority, double-blind, prospective, radiographic guidance
- Superiority
- Double-blind
- Prospective
- Radiographic guidance
Primary result
As reported in the abstract
50% improvement in spontaneous NRS
PRP
6
events
CTC
5
events
Secondary outcomes
Pain · 3, 6, or 12 months
- No statistically significant differences
Function (ODI) · 3 months
- Statistically significant difference observed in the PRP group
Satisfaction
- No significant differences between groups
Safety
- Transient adverse effects — PRP
- 1 events
- Transient adverse effects — Patients with transient adverse effects, total
- 4
Original publication
Platelet-rich plasma versus corticosteroids in facet joint syndrome: A controlled, randomized, double-blind study. Joint Bone Spine. Published 1 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →