Fibromyalgia & musculoskeletal pain
Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes
Authors' conclusion
These findings emphasize the potential value of assessing visual sensitivity to identify pain mechanisms across different diagnostic categories.
Study context
- Population
- Individuals with chronic nociceptive pain (hip OA, chronic pelvic pain, RA, PsA), FM and pain-free controls
- Exposure
- Visual sensitivity across chronic nociceptive pain conditions vs FM and pain-free controls; visual sensitivity as predictor of surgical nonresponse
- Outcome
- Visual sensitivity (perceived brightness to experimental visual stimulation) and lack of analgesic response after surgery
- Follow-up
- 6 months after surgery
Main finding
As reported in the abstract
- Participants across all pain conditions reported greater perceived brightness to visual stimulation vs controls
- Increased visual sensitivity independently predicted nonresponsiveness to surgery; experimental pressure pain sensitivity did not
- Higher self-reported FM symptom severity predicted lack of response to arthroplasty and hysterectomy
- Visual sensitivity and FM symptom severity together predicted greater variance in responder status than either alone
Observational data: associations, not effects.
Original publication
Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes. Arthritis Rheumatol. Published 23 March 2026. doi:10. 1002/ art. 70042
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