Vasculitis & polymyalgia rheumatica
Venous ulcers in Behçet syndrome
Authors' conclusion
Leg ulcers are challenging complications of DVT in BS and represent an unmet medical need.
Study context
- Population
- Behçet's syndrome (BS) patients with stasis ulcers among patients with vascular involvement, multidisciplinary centre, January 2021–July 2022of 310 with vascular involvement
- Participants
- 63 patients
- Outcome
- Clinical and histopathological characteristics, treatment modalities and outcomes of stasis ulcers
Methodological detailssingle multidisciplinary centre
- Single multidisciplinary centre
Main finding
As reported in the abstract
Stasis ulcer characteristics and outcomes
- Active ulcers at evaluation
- 35 (56 %)
- Ulcers healed imminently
- 44 %
- Median healing time
- 6 months
- Median time from vascular onset to ulcer
- 3 years
- Total ulcers
- 202
- Median ulcer size
- 3 cm
- Localised in gaiter region
- 72 %
- Histopathology favouring stasis dermatitis
- 67 % (14/21)
- Ulcers unhealed despite intensive therapy
- 17 %
- Recurrence rate
- 73 %
- Median follow-up
- 16.8 years
Observational data: associations, not effects.
Further findings
Treatments received
%
- Biological DMARDs
- 75
- Non-biological DMARDs
- 97
- Steroids
- 94
Original publication
Venous ulcers in Behçet syndrome. Semin Arthritis Rheum. Published 28 January 2025. doi:10.
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