Autoinflammatory & rare systemic diseases
Validation of systemic Juvenile Arthritis Disease Activity Score 10 in adults with Still’s disease
Authors' conclusion
The present study supports the external validity of the sJADAS10 in adults with SD.
Study context
- Population
- Adult patients with Still's disease followed in one reference centre
- Participants
- 129 visits
- Comparison
- sJADAS10 vs 4 other disease activity measures for adult SD, against Rosina definitions as reference
- Outcome
- Agreement (weighted Cohen's kappa) between disease states by sJADAS10 and the reference; discriminative power by ROC curves
Methodological detailssingle-centre, validation study
- Single-centre
- Validation study
Performance
As reported in the abstract
| Test or model | wKappa | Accuracy | AUC (inactive disease (ID)) | AUC (ID/low disease activity (LDA)) |
|---|---|---|---|---|
| sJADAS10 | 0.70 | 0.77 | 0.94 | 0.97 |
sJADAS10
wKappa0.70
Accuracy0.77
AUC (inactive disease (ID))0.94
AUC (ID/low disease activity (LDA))0.97
Further findings
Disease states by reference (visits)
- ID
- 38
- LDA
- 19
- Moderate disease activity (MDA)
- 33
- High disease activity (HDA)
- 39
Original publication
Validation of systemic Juvenile Arthritis Disease Activity Score 10 in adults with Still’s disease. Ann Rheum Dis. Published 4 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →