Urological cancer risk in patients with rheumatoid arthritis compared to matched controls: a nationwide cohort study
Main finding · Kidney cancerResult — go to the resultAdjusted hazard ratio 1.34 95% CI 1.04–1.78Authors' conclusion
RA patients have a higher risk of kidney cancer than the general population.
Study context
- Population
- Korean National Health Insurance System database (2010–2020): patients with rheumatoid arthritis (RA) and a 1:5 matched non-RA population
- Exposure
- RA vs matched non-RA population
- Outcome
- Newly diagnosed urological cancer (kidney, bladder, prostate, testicular)
Methodological detailsnationwide, 1:5 matched, Cox proportional hazards regression adjusting for potential confounders
- Nationwide
- 1:5 matched
- Cox proportional hazards regression adjusting for potential confounders
Main finding
Kidney cancer
Adjusted hazard ratio
1.34
95% CI 1.04–1.78
RAvs Non-RA
aHR 1.34 (95% CI 1.04–1.78)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| Kidney cancer in women (subgroup) | 1.57 (1.10–2.24) | |
| Bladder cancer | 1.24 (0.95–1.62) | |
| Prostate cancer | 1.13 (0.94–1.35) | |
| Testicular cancer | 2.31 (0.44–12.20) | |
| 0.050.21520Adjusted hazard ratio (log scale) |
Urological cancer risk by serological status
- No significant difference in urological cancer risk according to serological status
Original publication
Urological cancer risk in patients with rheumatoid arthritis compared to matched controls: a nationwide cohort study. Rheumatology (Oxford). Published 14 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →