Rheumatoid arthritis

Sustained exposure to low- and high-income status and risk of all-cause mortality in individuals with rheumatoid arthritis: a population-based retrospective cohort study from 2010 to 2020

RMD OpenPublished Retrospective cohort study

Authors' conclusion

Persistent low-income status increases mortality risk among younger patients with RA, a group often overlooked by policy interventions.

Study context

Population
Korean adults aged ≥40 years newly diagnosed with rheumatoid arthritis (RA) between 2010 and 2017, followed through 31 December 2020
Participants
50,600 adults
Exposure
Cumulative years in low- or high-income status over the 5 years preceding RA diagnosis
Outcome
All-cause mortality
Methodological detailspopulation-based, nationally representative, Cox proportional hazards models, stratified analysis
  • Population-based
  • Nationally representative
  • Cox proportional hazards models
  • Stratified analysis

Main finding

As reported in the abstract

All-cause mortality, by age group
Adjusted hazard ratio (95% CI)
5-year high-income exposure, age <65 years
0.50(0.38–0.64)
5-year high-income exposure, age ≥65 years
0.74(0.62–0.88)

Observational data: associations, not effects.

Further findings

Effect modification by rural residence

Rural residence further amplified the adverse effects of prolonged low-income exposure

Original publication

Sustained exposure to low- and high-income status and risk of all-cause mortality in individuals with rheumatoid arthritis: a population-based retrospective cohort study from 2010 to 2020. RMD Open. Published 2 April 2026. doi:10.1136/rmdopen-2025-006345

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