Rheumatoid arthritis

Understanding the use of thermography and its ability to predict ultrasound-detected joint inflammation at the metacarpophalangeal joint in patients with rheumatoid arthritis

Scand J RheumatolPublished Cross-sectional study

Authors' conclusion

Thermographic temperatures reflect ultrasound-detected joint inflammation, and appear useful in predicting PD vascularity at the MCPJs of patients with RA.

Study context

Population
Patients with rheumatoid arthritis (RA); Metacarpophalangeal joints (MCPJs) of each hand810 joints
Participants
81 patients
Exposure
Summed thermographic temperatures vs summed ultrasound (power Doppler (PD) and grey-scale (GS)) scores at the MCPJs
Outcome
Correlation of summed thermographic temperatures with summed PD and GS scores, and their ability to predict summed PD score ≥ 1 and summed GS score ≥ 18
Methodological detailsROC curve analysis, correlation and simple linear regression
  • ROC curve analysis
  • Correlation and simple linear regression

Main finding

As reported in the abstract

Correlation coefficients, summed thermographic temperatures with summed PD score (all p < 0.05)
0.45 to 0.52
Correlation coefficients, summed thermographic temperatures with summed GS score (all p < 0.05)
0.26 to 0.29
Regression coefficients, PD (p < 0.05)
0.094 to 0.137
Regression coefficients, GS (p < 0.05)
0.058 to 0.086
AUC, bilateral MCPJs, predicting summed PD score ≥ 1
0.80 to 0.82
AUC, bilateral MCPJs, predicting summed GS score ≥ 18
0.65 to 0.66

Observational data: associations, not effects.

Further findings

Intraobserver reliability (ICC), 45 baseline MCPJs resegmented > 2 weeks apart

ICC values excellent
all > 0.90
  • Single observer

Original publication

Understanding the use of thermography and its ability to predict ultrasound-detected joint inflammation at the metacarpophalangeal joint in patients with rheumatoid arthritis. Scand J Rheumatol. Published 29 August 2025. doi:10.1080/03009742.2025.2548061

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