Spondyloarthritis & psoriatic arthritis
Ultrasound for assessing disease activity and structural damage in psoriatic arthritis: the UPsA scores from a multicentre study by the Italian Society of Rheumatology
Authors' conclusion
The UPsA scores underwent internal validation and demonstrated responsiveness, representing valuable tools to assess PsA activity and damage.
Study context
- Population
- Patients with psoriatic arthritis (PsA) across 19 Italian centresbaseline and 6-month data
- Participants
- 312 patients
- Outcome
- UPsA scores: values, construct validity and sensitivity to change
Methodological detailsmulticentre, factor analysis, US of 42 joints, 36 tendons, 12 entheses and 2 bursae by trained sonographers; composite scores range 0-10
- Multicentre
- Factor analysis
- US of 42 joints, 36 tendons, 12 entheses and 2 bursae by trained sonographers; composite scores range 0-10
Performance
As reported in the abstract
- UPsA activity score, mean (SD)
- 3.7 (SD 1.86)
- UPsA activity score correlation with DAPSA (rs)
- 0.42
- UPsA activity score correlation with 68-tender joint count (rs)
- 0.31
- UPsA activity score correlation with 66-swollen joint count (rs)
- 0.45; all P < .001
- UPsA damage score, mean (SD)
- 4.1 (SD 2.26)
- UPsA damage score correlation with modified Sharp-van der Heijde score (rs)
- 0.36, P < .001
- UPsA activity score sensitivity to change overall (standardised response mean (SRM))
- 0.63
- UPsA activity score responsiveness in patients achieving MDA (SRM)
- 1.03
- sUPsA information retained from full score
- 90%
Original publication
Ultrasound for assessing disease activity and structural damage in psoriatic arthritis: the UPsA scores from a multicentre study by the Italian Society of Rheumatology. Ann Rheum Dis. Published 28 November 2025. doi:10.
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