Spondyloarthritis & psoriatic arthritis
Sternoclavicular joint involvement in psoriatic arthritis: a hidden indicator of disease severity
Authors' conclusion
SCJ involvement is an underrecognized but clinically meaningful manifestation of PsA, associated with greater disease burden and enthesitis, often requiring escalation to advanced therapies.
Study context
- Population
- Patients with PsA in the Gladman Krembil Psoriatic Arthritis Program
- Participants
- 1,737 patients
- Outcome
- Prevalence of SCJ involvement (tender and/or swollen SCJ) and its clinical associations
Methodological detailsanalysis of prospectively collected data, longitudinal cohort, univariable and multivariable generalized estimating equation models
- Analysis of prospectively collected data
- Longitudinal cohort
- Univariable and multivariable generalized estimating equation models
Main finding
As reported in the abstract
SCJ involvement (prevalence) · ever over follow-up
Sternoclavicular joint (SCJ) involvement
182
10.5%
Clinically swollen SCJs
36
2.1%
SCJ involvement present at enrolment (baseline), among affected individuals
33.1%
Observational data: associations, not effects.
Further findings
Associations with SCJ involvement, univariable analyses (OR, 95% CI)
- Higher swollen joint count (SJC)
- OR 1.142, 95% CI 1.08-1.16
- Dactylitis
- 4.51, 2.02-10.05
- Enthesitis
- 6.74, 3.45-13.15
- No significant associations with sex, disease duration, axial and nail disease, PASI, pustular psoriasis or HLA markers
Associations with SCJ swelling, multivariable analysis (OR, 95% CI)
- Higher SJC
- 1.08, 1.03-1.14
- Enthesitis
- 4.54, 1.98-10.45
- Dactylitis
- 4.54, 1.98-10.45
- Lower b/tsDMARD use
- 0.30, 0.10-0.88
Original publication
Sternoclavicular joint involvement in psoriatic arthritis: a hidden indicator of disease severity. Rheumatology (Oxford). Published 24 November 2025. doi:10.
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