Spondyloarthritis & psoriatic arthritis
Increased risk of psoriatic arthritis in patients with familial Mediterranean fever: a population-based cohort study
Main finding · Incident PsAResult — go to the resultAdjusted hazard ratio 3.52 95% CI 2.48–5.0Authors' conclusion
FMF is associated with increased risk of developing PsA
Study context
- Population
- Adults aged ≥18 in a large Mediterranean healthcare provider (∼4.9 million members), January 2010–December 2023matched cohort
- Participants
- 9,736 vs 97,360
- Exposure
- Familial Mediterranean fever (FMF) treated with colchicine vs matched controls without FMF
- FMFn = 9,736
- Controlsn = 97,360reference
- Outcome
- Incident PsA
Methodological detailspopulation-based, frequency matched by age and sex (1:10), Cox proportional hazard regression
- Population-based
- Frequency matched by age and sex (1:10)
- Cox proportional hazard regression
Main finding
As reported in the abstract
Adjusted hazard ratio
3.52
95% CI 2.48–5.0
Events by group
FMF
43
events
Controls
119
events
FMFvs Controls
aHR 3.52 (95% CI 2.48–5.0)
Observational data: associations, not effects.
Original publication
Increased risk of psoriatic arthritis in patients with familial Mediterranean fever: a population-based cohort study. Rheumatology (Oxford). Published 21 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →