Spondyloarthritis & psoriatic arthritis
Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis and Persistent Pain: A Randomized Controlled Trial
Primary result · Change in MPI pain-related life interferenceResult — go to the resultβ −0.36 95% CI −0.73 to 0.01Authors' conclusion
The ACT app demonstrated a meaningful reduction in pain-related life interference
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) with persistent pain despite stable pharmacological therapy44 in intervention group (IG) actively used app
- Participants
- 136 patients
- Comparison
- And commitment therapy (ACT) app vs standard of care
- IGn = 73
- Standard of care (SOC)n = 63reference
- Primary endpoint
- Multidimensional Pain Inventory (MPI) pain-related life interference
- Follow-up
- 12 weeks
Methodological detailsunblinded, multicentric
- Unblinded
- Multicentric
Primary result
Change in MPI pain-related life interference
β
−0.36
95% CI −0.73 to 0.01
As reported in the abstract
Secondary outcomes
| Outcome | IG | β (95% CI) |
|---|---|---|
| Change in affective distress related to the disease · 12 weeksGreater improvement vs SOC; linear model | −0.4 (−0.84 to 0.03) | |
| Completion of all ACT app lessons | 43% |
- Completion of all ACT app lessons: among the 44 active users
Original publication
Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis and Persistent Pain: A Randomized Controlled Trial. Arthritis Care Res (Hoboken). Published 18 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →